Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation
Abstract MYC upregulation is associated with multidrug refractory disease in patients with multiple myeloma (MM). We, isolated patient-derived MM cells with high MYC expression and discovered that NCOR2 was down-regulated in these cells. NCOR2 is a transcriptional coregulatory protein and its role i...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Publishing Group
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/b338d530f2da4568b81bbdf194813434 |
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