Doxorubicin–transferrin conjugate alters mitochondrial homeostasis and energy metabolism in human breast cancer cells

Abstract Doxorubicin (DOX) is considered one of the most powerful chemotherapeutic agents but its clinical use has several limitations, including cardiomyopathy and cellular resistance to the drug. By using transferrin (Tf) as a drug carrier, however, the adverse effects of doxorubicin as well as dr...

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Autores principales: Paulina Wigner, Krzysztof Zielinski, Magdalena Labieniec-Watala, Agnieszka Marczak, Marzena Szwed
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b33adf26b2264bd79ed3bafd26548ba8
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