Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver

Abstract Parenteral nutrition-associated cholestasis (PNAC) significantly limits the safety of intravenous parenteral nutrition (PN). Critically ill infants are highly vulnerable to PNAC-related morbidity and mortality, however the impact of hepatic immaturity on PNAC is poorly understood. We examin...

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Auteurs principaux: T. Hang Nghiem-Rao, Courtney Pfeifer, Michelle Asuncion, Joshua Nord, Daniel Schill, Kirthi Pulakanti, Shailendra B. Patel, Lisa A. Cirillo, Sridhar Rao
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b34671d9c6c646bb8f69da0849e3d014
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