Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya.

<h4>Background</h4>Single nucleotide polymorphisms (SNPs) in the dhfr and dhps genes are associated with sulphadoxine-pyrimethamine (SP) treatment failure and gametocyte carriage. This may result in enhanced transmission of mutant malaria parasites, as previously shown for chloroquine re...

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Autores principales: Mayke J A M Oesterholt, Michael Alifrangis, Colin J Sutherland, Sabah A Omar, Patrick Sawa, Christina Howitt, Louis C Gouagna, Robert W Sauerwein, Teun Bousema
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/b3b98ca949fb46a2a1c518955fc44f99
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