Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya.
<h4>Background</h4>Single nucleotide polymorphisms (SNPs) in the dhfr and dhps genes are associated with sulphadoxine-pyrimethamine (SP) treatment failure and gametocyte carriage. This may result in enhanced transmission of mutant malaria parasites, as previously shown for chloroquine re...
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Main Authors: | Mayke J A M Oesterholt, Michael Alifrangis, Colin J Sutherland, Sabah A Omar, Patrick Sawa, Christina Howitt, Louis C Gouagna, Robert W Sauerwein, Teun Bousema |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Online Access: | https://doaj.org/article/b3b98ca949fb46a2a1c518955fc44f99 |
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