Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics
Bioactive metabolites from plant and microbial extracts hold therapeutic potential. Here, the authors combine untargeted metabolomic arrays with flow cytometry-based single cell response profiling and identify metabolites with cell subset-specific activities in the bone marrow from an AML patient.
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Main Authors: | David C. Earl, P. Brent Ferrell, Nalin Leelatian, Jordan T. Froese, Benjamin J. Reisman, Jonathan M. Irish, Brian O. Bachmann |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/b3bcc8bdbb794beeb2a498e7912fa5bb |
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