The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Cryptococcus neoformans can cause fatal meningoencephalitis in patients with AIDS or other immunocompromising conditions. Current antifungals are suboptimal to treat this disease; therefore, novel targets and new therapies are needed. Previously, we have shown that chitosan is a critical co...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma. Xenia G. Ilagan, Maureen J. Donlin, Jennifer K. Lodge
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Cryptococcus neoformans
cAMP
chitosan
drug screening
flow cytometry
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b3cde10d9e614e4c8f1c4ec327805652
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares