The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
ABSTRACT Cryptococcus neoformans can cause fatal meningoencephalitis in patients with AIDS or other immunocompromising conditions. Current antifungals are suboptimal to treat this disease; therefore, novel targets and new therapies are needed. Previously, we have shown that chitosan is a critical co...
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| Auteurs principaux: | Brian T. Maybruck, Woei C. Lam, Charles A. Specht, Ma. Xenia G. Ilagan, Maureen J. Donlin, Jennifer K. Lodge |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2019
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/b3cde10d9e614e4c8f1c4ec327805652 |
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