Inhibition of hedgehog signaling decreases proliferation and clonogenicity of human mesenchymal stem cells.

Human mesenchymal stem cells (hMSC) have the ability to differentiate into osteoblasts, adipocytes and chondrocytes. We have previously shown that hMSC were endowed with a basal level of Hedgehog signaling that decreased after differentiation of these cells. Since hMSC differentiation is associated...

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Auteurs principaux: Magali Plaisant, Sophie Giorgetti-Peraldi, Marike Gabrielson, Agnes Loubat, Christian Dani, Pascal Peraldi
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/b3f91662e1404d1a88c2f4da9e6dea70
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