Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay

Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay

Abstract Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis. Specific binding and internalization of BoNT/A into neuronal cells is mediated by its bindin...

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Bibliographic Details
Main Authors: Nicholas G. James, Shiazah Malik, Bethany J. Sanstrum, Catherine Rhéaume, Ron S. Broide, David M. Jameson, Amy Brideau-Andersen, Birgitte S. Jacky
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b42c13adfc0c41cca508116cf7c6999f
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