Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting

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Tryptophan Metabolism in Bipolar Disorder in a Longitudinal Setting

Immune-mediated inflammatory processes and oxidative stress are involved in the aetiopathogenesis of bipolar disorder (BD) and weight-associated comorbidities. Tryptophan breakdown via indoleamine 2,3-dioxygenase-1 (IDO-1) along the kynurenine axis concomitant with a pro-inflammatory state was found...

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Bibliographic Details
Main Authors:	Frederike T. Fellendorf, Johanna M. Gostner, Melanie Lenger, Martina Platzer, Armin Birner, Alexander Maget, Robert Queissner, Adelina Tmava-Berisha, Cornelia A. Pater, Michaela Ratzenhofer, Jolana Wagner-Skacel, Susanne A. Bengesser, Nina Dalkner, Dietmar Fuchs, Eva Z. Reininghaus
Format:	article
Language:	EN
Published:	MDPI AG 2021
Subjects:	bipolar disorder psychoneuroimmunology kynurenine to tryptophan ratio tryptophan metabolism IDO-1 Therapeutics. Pharmacology RM1-950
Online Access:	https://doaj.org/article/b47b6454846a4d7cae08521cf3d751be
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