A DNA-centered explanation of the DNA polymerase translocation mechanism

Abstract DNA polymerase couples chemical energy to translocation along a DNA template with a specific directionality while it replicates genetic information. According to single-molecule manipulation experiments, the polymerase-DNA complex can work against loads greater than 50 pN. It is not known,...

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Autor principal: J. Ricardo Arias-Gonzalez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b4823d6a736049069ae21af33324cfae
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