A DNA-centered explanation of the DNA polymerase translocation mechanism
Abstract DNA polymerase couples chemical energy to translocation along a DNA template with a specific directionality while it replicates genetic information. According to single-molecule manipulation experiments, the polymerase-DNA complex can work against loads greater than 50 pN. It is not known,...
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| Format: | article |
| Language: | EN |
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Nature Portfolio
2017
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| Online Access: | https://doaj.org/article/b4823d6a736049069ae21af33324cfae |
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