Bodiniosides S–Y, Seven New Triterpenoid Saponins from <i>Elsholtzia bodinieri</i> and Their Anti-Influenza Activities
Investigation of the n-BuOH extract of the aerial parts of <i>Elsholtzia bodinieri</i> led to the isolation of seven new triterpenoid saponins, Bodiniosides S–Y (<b>1</b>–<b>7</b>, resp.). Their strictures were elucidated on the basis of spectroscopic techniques,...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
MDPI AG
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/b4ab26f52e9b4f7f98318fde13d2a1ab |
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| Summary: | Investigation of the n-BuOH extract of the aerial parts of <i>Elsholtzia bodinieri</i> led to the isolation of seven new triterpenoid saponins, Bodiniosides S–Y (<b>1</b>–<b>7</b>, resp.). Their strictures were elucidated on the basis of spectroscopic techniques, including HSQC, HSBC, and HSQC–TOCSY experiments, together with acid hydrolysis and GC analysis. The anti-influenza activities of compounds <b>1</b>–<b>7</b> were evaluated against A/WSN/33/2009 (H1N1) virus in MDCK cells. The results showed that compounds <b>2</b> and <b>5</b> exhibited moderate anti-influenza activities against A/WSN/33/2009 (H1N1), with inhibition rates of 35.33% and 24.08%, respectively. |
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