Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice
Wang et al. report that deficiency of dynamin-related protein 1, which controls mitochondrial fission, accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice. Thus, they highlight mitochondria dynamics dysfunction as a new mechanism of liver disease development.
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Main Authors: | Lixiang Wang, Xin Li, Yuki Hanada, Nao Hasuzawa, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/b4b859d6ece348c3a063d390f5e00ce9 |
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