Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor

ABSTRACT The bacterial intracellular second messenger, cyclic dimeric GMP (c-di-GMP), regulates biofilm formation for many bacteria. The binding of c-di-GMP by the inner membrane protein LapD controls biofilm formation, and the LapD receptor is central to a complex network of c-di-GMP-mediated biofi...

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Bibliographic Details
Main Authors: David Giacalone, T. Jarrod Smith, Alan J. Collins, Holger Sondermann, Lori J. Koziol, George A. O’Toole
Format: article
Language:EN
Published: American Society for Microbiology 2018
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Online Access:https://doaj.org/article/b5011e19efcc4e4ab6d7916c4423498c
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