Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol.

The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane. To better understand Arb mechanism of action, we investigated its interactions with phospholipids and membrane peptides. We demonstrate that Arb associates with phosp...

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Autores principales: Elodie Teissier, Giorgia Zandomeneghi, Antoine Loquet, Dimitri Lavillette, Jean-Pierre Lavergne, Roland Montserret, François-Loïc Cosset, Anja Böckmann, Beat H Meier, François Penin, Eve-Isabelle Pécheur
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/b5018ec167664ed6b836c2e03b8ff3e2
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