Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol.

The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane. To better understand Arb mechanism of action, we investigated its interactions with phospholipids and membrane peptides. We demonstrate that Arb associates with phosp...

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Bibliographic Details
Main Authors: Elodie Teissier, Giorgia Zandomeneghi, Antoine Loquet, Dimitri Lavillette, Jean-Pierre Lavergne, Roland Montserret, François-Loïc Cosset, Anja Böckmann, Beat H Meier, François Penin, Eve-Isabelle Pécheur
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/b5018ec167664ed6b836c2e03b8ff3e2
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