MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis

Matsuzawa et al. show that adhesion-related molecules MAGI-1 and MAGI-3 localize partitioning defective-3 (Par-3) at apical junctional complexes of cells throughout the epithelial monolayer. This study provides insights into how tension distribution contributes to cellular contractility in epithelia...

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Auteurs principaux: Kenji Matsuzawa, Hayato Ohga, Kenta Shigetomi, Tomohiro Shiiya, Masanori Hirashima, Junichi Ikenouchi
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/b50312c314ed43189c30badc59145e94
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