MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis

Matsuzawa et al. show that adhesion-related molecules MAGI-1 and MAGI-3 localize partitioning defective-3 (Par-3) at apical junctional complexes of cells throughout the epithelial monolayer. This study provides insights into how tension distribution contributes to cellular contractility in epithelia...

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Autores principales:	Kenji Matsuzawa, Hayato Ohga, Kenta Shigetomi, Tomohiro Shiiya, Masanori Hirashima, Junichi Ikenouchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/b50312c314ed43189c30badc59145e94
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spelling	oai:doaj.org-article:b50312c314ed43189c30badc59145e942021-12-02T11:36:25ZMAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis10.1038/s42003-021-01874-z2399-3642https://doaj.org/article/b50312c314ed43189c30badc59145e942021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01874-zhttps://doaj.org/toc/2399-3642Matsuzawa et al. show that adhesion-related molecules MAGI-1 and MAGI-3 localize partitioning defective-3 (Par-3) at apical junctional complexes of cells throughout the epithelial monolayer. This study provides insights into how tension distribution contributes to cellular contractility in epithelial tissue homeostasis.Kenji MatsuzawaHayato OhgaKenta ShigetomiTomohiro ShiiyaMasanori HirashimaJunichi IkenouchiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Kenji Matsuzawa Hayato Ohga Kenta Shigetomi Tomohiro Shiiya Masanori Hirashima Junichi Ikenouchi MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
description	Matsuzawa et al. show that adhesion-related molecules MAGI-1 and MAGI-3 localize partitioning defective-3 (Par-3) at apical junctional complexes of cells throughout the epithelial monolayer. This study provides insights into how tension distribution contributes to cellular contractility in epithelial tissue homeostasis.
format	article
author	Kenji Matsuzawa Hayato Ohga Kenta Shigetomi Tomohiro Shiiya Masanori Hirashima Junichi Ikenouchi
author_facet	Kenji Matsuzawa Hayato Ohga Kenta Shigetomi Tomohiro Shiiya Masanori Hirashima Junichi Ikenouchi
author_sort	Kenji Matsuzawa
title	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
title_short	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
title_full	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
title_fullStr	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
title_full_unstemmed	MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
title_sort	magis regulate apkc to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b50312c314ed43189c30badc59145e94
work_keys_str_mv	AT kenjimatsuzawa magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis AT hayatoohga magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis AT kentashigetomi magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis AT tomohiroshiiya magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis AT masanorihirashima magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis AT junichiikenouchi magisregulateapkctoenablebalanceddistributionofintercellulartensionforepithelialsheethomeostasis
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MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis

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