MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
Matsuzawa et al. show that adhesion-related molecules MAGI-1 and MAGI-3 localize partitioning defective-3 (Par-3) at apical junctional complexes of cells throughout the epithelial monolayer. This study provides insights into how tension distribution contributes to cellular contractility in epithelia...
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Autores principales: | Kenji Matsuzawa, Hayato Ohga, Kenta Shigetomi, Tomohiro Shiiya, Masanori Hirashima, Junichi Ikenouchi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b50312c314ed43189c30badc59145e94 |
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