Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids
The relative contribution of fallopian tube (FT) or ovarian surface epithelium (OSE) to high-grade serous ovarian cancer (HG-SOC) development is unclear. Here, the authors establish organoid models from murine oviductal and OSE tissues that allow cancer modeling via CRISPR-Cas9 genome editing, and r...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/b561dc387d334f75b89e8a94ccc8b593 |
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