Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
The significance of rare and de novo variants in bipolar disorder is not well understood. Here, the authors have analyzed whole exome/genome data from trios to identify deleterious de novo variants associated with bipolar disorder.
Saved in:
Main Authors: | Masaki Nishioka, An-a Kazuno, Takumi Nakamura, Naomi Sakai, Takashi Hayama, Kumiko Fujii, Koji Matsuo, Atsuko Komori, Mizuho Ishiwata, Yoshinori Watanabe, Takashi Oka, Nana Matoba, Muneko Kataoka, Ahmed N. Alkanaq, Kohei Hamanaka, Takashi Tsuboi, Toru Sengoku, Kazuhiro Ogata, Nakao Iwata, Masashi Ikeda, Naomichi Matsumoto, Tadafumi Kato, Atsushi Takata |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/b566dcdf10494a0cb75a52d15029cc4f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
by: Atsushi Takata, et al.
Published: (2017) -
A marked effect of electroconvulsive stimulation on behavioral aberration of mice with neuron-specific mitochondrial DNA defects.
by: Takaoki Kasahara, et al.
Published: (2008) -
Clinically-relevant postzygotic mosaicism in parents and children with developmental disorders in trio exome sequencing data
by: C. F. Wright, et al.
Published: (2019) -
Clinical relevance of postzygotic mosaicism in Cornelia de Lange syndrome and purifying selection of NIPBL variants in blood
by: Ana Latorre-Pellicer, et al.
Published: (2021) -
Prezygotic and Postzygotic Control of Uniparental Mitochondrial DNA Inheritance in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
by: Rachana Gyawali, et al.
Published: (2013)