Esterase‐Activatable and Glutathione‐Responsive Triptolide Nano‐Prodrug for the Eradication of Pancreatic Cancer
Triptolide (TPL) is a small molecule isolated from a traditional Chinese herb Tripterygium wilfordii Hook F and shows excellent anticancer effect for pancreatic cancer cells. However, the poor water solubility ad severe liver toxicity of TPL hindered its clinical application. Herein, TPL is covalent...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Wiley-VCH
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/b575ab66e38541609a17951601968fce |
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