Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates

SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.

Guardado en:

Detalles Bibliográficos
Autores principales:	Nik Franko, Ana Palma Teixeira, Shuai Xue, Ghislaine Charpin-El Hamri, Martin Fussenegger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b5aed737c2c545b2be5f551a0d14a25f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b5aed737c2c545b2be5f551a0d14a25f
record_format	dspace
spelling	oai:doaj.org-article:b5aed737c2c545b2be5f551a0d14a25f2021-11-28T12:32:34ZDesign of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates10.1038/s41467-021-27072-32041-1723https://doaj.org/article/b5aed737c2c545b2be5f551a0d14a25f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27072-3https://doaj.org/toc/2041-1723SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.Nik FrankoAna Palma TeixeiraShuai XueGhislaine Charpin-El HamriMartin FusseneggerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nik Franko Ana Palma Teixeira Shuai Xue Ghislaine Charpin-El Hamri Martin Fussenegger Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
description	SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.
format	article
author	Nik Franko Ana Palma Teixeira Shuai Xue Ghislaine Charpin-El Hamri Martin Fussenegger
author_facet	Nik Franko Ana Palma Teixeira Shuai Xue Ghislaine Charpin-El Hamri Martin Fussenegger
author_sort	Nik Franko
title	Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
title_short	Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
title_full	Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
title_fullStr	Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
title_full_unstemmed	Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
title_sort	design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b5aed737c2c545b2be5f551a0d14a25f
work_keys_str_mv	AT nikfranko designofmodularautoproteolyticgeneswitchesresponsivetoanticoronavirusdrugcandidates AT anapalmateixeira designofmodularautoproteolyticgeneswitchesresponsivetoanticoronavirusdrugcandidates AT shuaixue designofmodularautoproteolyticgeneswitchesresponsivetoanticoronavirusdrugcandidates AT ghislainecharpinelhamri designofmodularautoproteolyticgeneswitchesresponsivetoanticoronavirusdrugcandidates AT martinfussenegger designofmodularautoproteolyticgeneswitchesresponsivetoanticoronavirusdrugcandidates
_version_	1718407914488594432

Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates

Ejemplares similares