Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates

SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.

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Autores principales: Nik Franko, Ana Palma Teixeira, Shuai Xue, Ghislaine Charpin-El Hamri, Martin Fussenegger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b5aed737c2c545b2be5f551a0d14a25f
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