Design of modular autoproteolytic gene switches responsive to anti-coronavirus drug candidates
SARS-CoV-2 proteases are key targets for anti-viral drug development. Here the authors present modular tunable autoproteolytic gene switches for virus free cell culture screening of inhibitors.
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Main Authors: | Nik Franko, Ana Palma Teixeira, Shuai Xue, Ghislaine Charpin-El Hamri, Martin Fussenegger |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/b5aed737c2c545b2be5f551a0d14a25f |
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