Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Mechanistic studies of Drosophila lymph gland hematopoiesis are limited by the availability of cell-type-specific markers. Using a combination of bulk RNA-Seq of FACS-sorted cells, single-cell RNA-Seq, and genetic dissection, we identify new blood cell subpopulations along a developmental trajectory...

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Autores principales: Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
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Acceso en línea:https://doaj.org/article/b5c668a8e4d744bdbdb753ddb87caae0
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