Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine.

We used mouse models of pneumococcal colonization and disease combined with full genome sequencing to characterize three major drug resistant clones of S. pneumoniae that were recovered from the nasopharynx of PCV7-immunized children in Portugal. The three clones--serotype 6A (ST2191), serotype 15A...

Full description

Saved in:
Bibliographic Details
Main Authors: Nelson Frazão, N Luisa Hiller, Evan Powell, Josh Earl, Azad Ahmed, Raquel Sá-Leão, Hermínia de Lencastre, Garth D Ehrlich, Alexander Tomasz
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/b5d390fb01c2446680951d62691560dd
Tags: Add Tag
No Tags, Be the first to tag this record!