Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity

Design, synthesis and biological evaluation of N-oxide derivatives with potent in vivo antileishmanial activity

Show other versions (1)

Leishmaniasis is a neglected disease that affects 12 million people living mainly in developing countries. Herein, 24 new N-oxide-containing compounds were synthesized followed by in vitro and in vivo evaluation of their antileishmanial activity. Compound 4f, a furoxan derivative, was particularly r...

Full description

Saved in:
Bibliographic Details
Main Authors: Leandro da Costa Clementino, Guilherme Felipe Santos Fernandes, Igor Muccilo Prokopczyk, Wilquer Castro Laurindo, Danyelle Toyama, Bruno Pereira Motta, Amanda Martins Baviera, Flávio Henrique-Silva, Jean Leandro dos Santos, Marcia A. S. Graminha
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b5f6d88a45434c8e983019e31e61b2e6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/b5f6d88a45434c8e983019e31e61b2e6

Similar Items