An open-source automated PEG precipitation assay to measure the relative solubility of proteins with low material requirement

Abstract The solubility of proteins correlates with a variety of their properties, including function, production yield, pharmacokinetics, and formulation at high concentrations. High solubility is therefore a key requirement for the development of protein-based reagents for applications in life sci...

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Autores principales: Marc Oeller, Pietro Sormanni, Michele Vendruscolo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b5f7828ff8824c158a7da76797f5c5ae
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