A lateral signalling pathway coordinates shape volatility during cell migration

Migrating cells display dynamic morphologies that are coordinated by signalling pathways. Here the authors identify a lateral signalling pathway, comprised of the planar cell polarity protein Pk1 and Arhgap21/23, that regulates fluctuations in cell shape during productive cell migration.

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Autores principales: Liang Zhang, Valbona Luga, Sarah K. Armitage, Martin Musiol, Amy Won, Christopher M. Yip, Sergey V. Plotnikov, Jeffrey L. Wrana
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/b635d2a26aed42ca9f20cdfb111a9045
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