A lateral signalling pathway coordinates shape volatility during cell migration

A lateral signalling pathway coordinates shape volatility during cell migration

Migrating cells display dynamic morphologies that are coordinated by signalling pathways. Here the authors identify a lateral signalling pathway, comprised of the planar cell polarity protein Pk1 and Arhgap21/23, that regulates fluctuations in cell shape during productive cell migration.

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Autores principales: Liang Zhang, Valbona Luga, Sarah K. Armitage, Martin Musiol, Amy Won, Christopher M. Yip, Sergey V. Plotnikov, Jeffrey L. Wrana
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/b635d2a26aed42ca9f20cdfb111a9045
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spelling oai:doaj.org-article:b635d2a26aed42ca9f20cdfb111a90452021-12-02T14:38:54ZA lateral signalling pathway coordinates shape volatility during cell migration10.1038/ncomms117142041-1723https://doaj.org/article/b635d2a26aed42ca9f20cdfb111a90452016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11714https://doaj.org/toc/2041-1723Migrating cells display dynamic morphologies that are coordinated by signalling pathways. Here the authors identify a lateral signalling pathway, comprised of the planar cell polarity protein Pk1 and Arhgap21/23, that regulates fluctuations in cell shape during productive cell migration.Liang ZhangValbona LugaSarah K. ArmitageMartin MusiolAmy WonChristopher M. YipSergey V. PlotnikovJeffrey L. WranaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Liang Zhang
Valbona Luga
Sarah K. Armitage
Martin Musiol
Amy Won
Christopher M. Yip
Sergey V. Plotnikov
Jeffrey L. Wrana
A lateral signalling pathway coordinates shape volatility during cell migration
description Migrating cells display dynamic morphologies that are coordinated by signalling pathways. Here the authors identify a lateral signalling pathway, comprised of the planar cell polarity protein Pk1 and Arhgap21/23, that regulates fluctuations in cell shape during productive cell migration.
format article
author Liang Zhang
Valbona Luga
Sarah K. Armitage
Martin Musiol
Amy Won
Christopher M. Yip
Sergey V. Plotnikov
Jeffrey L. Wrana
author_facet Liang Zhang
Valbona Luga
Sarah K. Armitage
Martin Musiol
Amy Won
Christopher M. Yip
Sergey V. Plotnikov
Jeffrey L. Wrana
author_sort Liang Zhang
title A lateral signalling pathway coordinates shape volatility during cell migration
title_short A lateral signalling pathway coordinates shape volatility during cell migration
title_full A lateral signalling pathway coordinates shape volatility during cell migration
title_fullStr A lateral signalling pathway coordinates shape volatility during cell migration
title_full_unstemmed A lateral signalling pathway coordinates shape volatility during cell migration
title_sort lateral signalling pathway coordinates shape volatility during cell migration
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/b635d2a26aed42ca9f20cdfb111a9045
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