Monocyte-dependent co-stimulation of cytokine induction in human γδ T cells by TLR8 RNA ligands

Abstract Human Vγ9Vδ2 T cells recognize pyrophosphates produced by microbes and transformed cells and play a role in anti-infective immunity and tumor surveillance. Toll-like receptors (TLR) are pattern recognition receptors in innate immune cells which sense microbial structures including nucleic a...

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Autores principales: Ruben Serrano, Christoph Coch, Christian Peters, Gunther Hartmann, Daniela Wesch, Dieter Kabelitz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b641f3f4ca8948f881ad01de1b5a59b8
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