Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses
Sun et al. show that hepatitis C virus or free-fatty acids increase lipid droplets and apolipoprotein J (ApoJ) expression while ApoJ silencing alleviates hepatic lipid accumulation. This study suggests that hepatic ApoJ may activate sterol O-acyltransferase 2 to supply cholesteryl-ester for lipid lo...
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| Autores principales: | , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/b6481110f1c447b693020f4fbbc72f40 |
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