Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites.

Immunization with radiation attenuated Plasmodium sporozoites (RAS) elicits sterile protective immunity against sporozoite challenge in murine models and in humans. Similarly to RAS, the genetically attenuated sporozoites (GAPs) named uis3(-), uis4(-) and P36p(-) have arrested growth during the live...

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Bibliographic Details

Main Authors:	Kota Arun Kumar, Peter Baxter, Alice S Tarun, Stefan H I Kappe, Victor Nussenzweig
Format:	article
Language:	EN
Published:	Public Library of Science (PLoS) 2009
Subjects:	Medicine R Science Q
Online Access:	https://doaj.org/article/b651b80add02401999d495eca72eea7a
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