Reverse C-glycosidase reaction provides C-nucleotide building blocks of xenobiotic nucleic acids
C-nucleosides are analogues of the canonical N-nucleosides and, despite their synthetic value, biocatalysis has not targeted them yet. Here, the authors report a pseudouridine monophosphate C-glycosidase enzyme for selective 5-β-C-glycosylation of uracil and its derivatives from pentose 5- phosphate...
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2020
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Acceso en línea: | https://doaj.org/article/b67940dc96204bd1a7efa6244b05d5f4 |
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