Cnot3 enhances human embryonic cardiomyocyte proliferation by promoting cell cycle inhibitor mRNA degradation

Abstract Uncovering the molecular basis of mammalian cardiomyocyte proliferation may eventually lead to better approaches for heart regeneration. Compared to extensively-studied transcriptional regulation, the roles of posttranscriptional regulation in cardiac cell fate decisions remain largely unkn...

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Autores principales: Bingying Zhou, Junwei Liu, Zongna Ren, Fang Yao, Jingwei Ma, Jiangping Song, Brian Bennett, Yisong Zhen, Li Wang, Guang Hu, Shengshou Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b681699cad744c04b8dd4fa67ab9317c
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