Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.

RING finger protein 43 (RNF43), an E3-type ubiquitin ligase, is frequently up-regulated in human colorectal cancer. It has been shown that expression of RNF43 is regulated by the Wnt-signaling pathway. However the regulatory region(s) for its transcriptional activation has not been clarified. In thi...

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Autores principales: Norihiko Takahashi, Kiyoshi Yamaguchi, Tsuneo Ikenoue, Tomoaki Fujii, Yoichi Furukawa
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/b690e06c1873474285a0753fa4c315aa
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