Persistent autoantibody-production by intermediates between short-and long-lived plasma cells in inflamed lymph nodes of experimental epidermolysis bullosa acquisita.

Autoantibodies are believed to be maintained by either the continuous generation of short-lived plasma cells in secondary lymphoid tissues or by long-lived plasma cells localized in bone marrow and spleen. Here, we show in a mouse model for the autoimmune blistering skin disease epidermolysis bullos...

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Auteurs principaux: Benjamin Tiburzy, Martin Szyska, Hiroaki Iwata, Navina Chrobok, Upasana Kulkarni, Misa Hirose, Ralf J Ludwig, Kathrin Kalies, Jürgen Westermann, David Wong, Rudolf Armin Manz
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/b69bedf208664ce085a7c7d464091d60
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