Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration

How cells migrate in fibrous tissues is still poorly understood. Here, with synthetic 3D fibre matrices of controlled alignment and stiffness, the authors report that cells in stiff matrices move slowly and continuously, but in softer, deformable matrices cells can rapidly slingshot forward via stre...

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Bibliographic Details
Main Authors: William Y. Wang, Christopher D. Davidson, Daphne Lin, Brendon M. Baker
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/b6d65b2bec4e4f619c3788aad89acbbf
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