Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.

<h4>Background</h4>Chronic inflammation and oxidative stress are key features of chronic obstructive pulmonary disease (COPD). Oxidative stress enhances COPD inflammation under the control of the pro-inflammatory redox-sensitive transcription factor nuclear factor-kappaB (NF-κB). Histone...

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Bibliographic Details
Main Authors: Younis M Khan, Paul Kirkham, Peter J Barnes, Ian M Adcock
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/b6e773be28c1451d99fffa7e881c7161
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