CLCAs - a family of metalloproteases of intriguing phylogenetic distribution and with cases of substituted catalytic sites.

The zinc-dependent metalloproteases with His-Glu-x-x-His (HExxH) active site motif, zincins, are a broad group of proteins involved in many metabolic and regulatory functions, and found in all forms of life. Human genome contains more than 100 genes encoding proteins with known zincin-like domains....

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Autores principales: Anna Lenart, Małgorzata Dudkiewicz, Marcin Grynberg, Krzysztof Pawłowski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b6ef177ef9014ea3a0ccdd79f204bcff
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