An attempt to detect siRNA-mediated genomic DNA modification by artificially induced mismatch siRNA in Arabidopsis.

Although tremendous progress has been made in recent years in identifying molecular mechanisms of small interfering RNA (siRNA) functions in higher plants, the possibility of direct interaction between genomic DNA and siRNA remains an enigma. Such an interaction was proposed in the 'RNA cache&#...

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Autores principales: Yosuke Miyagawa, Jun Ogawa, Yuji Iwata, Nozomu Koizumi, Kei-ichiro Mishiba
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b70b24edd5934197b124dad16a8b4a6f
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