Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells

IL-15 signals through STAT5 to modulate natural killer (NK) cell maturation, function and homeostasis, but the specific contributions of STAT5 dimers and tetramers are still unclear. Here the authors show that, while STAT5 dimers are sufficient for NK development, STAT5 tetramers are essential for N...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jian-Xin Lin, Ning Du, Peng Li, Majid Kazemian, Tesfay Gebregiorgis, Rosanne Spolski, Warren J. Leonard
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/b737b1cb8b61414c848b3ccab3e8881b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!