Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.

<h4>Background</h4>Radiotherapy kills tumor-cells by inducing DNA double strand breaks (DSBs). However, the efficient repair of tumors frequently prevents successful treatment. Therefore, identifying new practical sensitizers is an essential step towards successful radiotherapy. In this...

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Autores principales: Dan Yan, Wooi Loon Ng, Xiangming Zhang, Ping Wang, Zhaobin Zhang, Yin-Yuan Mo, Hui Mao, Chunhai Hao, Jeffrey J Olson, Walter J Curran, Ya Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/b73c1458c96f4e3b9d79b60678b2b336
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