aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis

Squamous epithelia present actin-rich microridges on the apical surface, but the mechanism of their formation is not known. Here the authors show that, in zebrafish epidermis, the exclusion of the basolateral regulator Lgl from the apical domain by atypical protein kinase C prevents precocious elong...

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Auteurs principaux: Renuka Raman, Indraneel Damle, Rahul Rote, Shamik Banerjee, Chaitanya Dingare, Mahendra Sonawane
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/b7590a5713f845c58451d66693f083c7
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