Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

Abstract During obesity, macrophages can infiltrate metabolic tissues, and contribute to chronic low-grade inflammation, and mediate insulin resistance and diabetes. Recent studies have elucidated the metabolic role of JAK2, a key mediator downstream of various cytokines and growth factors. Our stud...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Harsh R. Desai, Tharini Sivasubramaniyam, Xavier S. Revelo, Stephanie A. Schroer, Cynthia T. Luk, Prashanth R. Rikkala, Adam H. Metherel, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Joshua A. Rapps, Rickvinder Besla, Clinton S. Robbins, Kay-Uwe Wagner, Richard P. Bazinet, Daniel A. Winer, Minna Woo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b77b851e7bc64e208ba3be8fd1060be7
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/b77b851e7bc64e208ba3be8fd1060be7

Ejemplares similares