Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect?

Eribulin activity in soft tissue sarcoma monolayer and three-dimensional cell line models: could the combination with other drugs improve its antitumoral effect?

Abstract Background Eribulin has shown antitumour activity in some soft tissue sarcomas (STSs), but it has only been approved for advanced liposarcoma (LPS). Methods In this study, we evaluated the effect of eribulin on proliferation, migration and invasion capabilities in LPS, leiomyosarcoma (LMS)...

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Bibliographic Details
Main Authors: Javier Escudero, Victoria Heredia-Soto, Yinyin Wang, Patricia Ruiz, Yingying Hu, Alejandro Gallego, Jose Juan Pozo-Kreilinger, Virginia Martinez-Marin, Alberto Berjon, Eduardo Ortiz-Cruz, Daniel Bernabeu, Jaime Feliu, Jing Tang, Andres Redondo, Marta Mendiola
Format: article
Language:EN
Published: BMC 2021
Subjects:
Eribulin
Sarcoma
Proliferation
Migration
Invasion
2D and 3D models
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Cytology
QH573-671
Online Access:https://doaj.org/article/b78e4f4455e240a4918e698b421f1608
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