Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.

Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.

Mother-to-infant transmission (MTIT) of HIV is a serious global health concern, with over 300,000 children newly infected in 2011. SIV infection of rhesus macaques (RMs) results in similar rates of MTIT to that of HIV in humans. In contrast, SIV infection of sooty mangabeys (SMs) rarely results in M...

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Auteurs principaux: Ann Chahroudi, Emily Cartwright, S Thera Lee, Maud Mavigner, Diane G Carnathan, Benton Lawson, Paul M Carnathan, Tayebeh Hashempoor, Megan K Murphy, Tracy Meeker, Stephanie Ehnert, Christopher Souder, James G Else, Joyce Cohen, Ronald G Collman, Thomas H Vanderford, Sallie R Permar, Cynthia A Derdeyn, Francois Villinger, Guido Silvestri
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/b7bad9f24d134b17a34838523bdd28a3
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